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Hoechst 34580 tetrahydrochloride, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.
Hoechst 34580 tetrahydrochloride, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 495 | 期货 | |
10 mg | ¥ 745 | 期货 | |
50 mg | ¥ 1,990 | 期货 | |
100 mg | ¥ 2,820 | 期货 | |
200 mg | 询价 | 期货 | |
500 mg | 询价 | 期货 |
产品描述 | Hoechst 34580 tetrahydrochloride, a cell-permeable fluorescent dye, is used for staining DNA and nuclei. |
体外活性 | Hoechst 34580 is a good candidate for treating Alzheimer's disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner. The IC50 is obtained by measuring the concentration of Hoechst 34580 while maintaining the Aβ42 concentration which gave 0.86±0.05 μM for Hoechst 34580. |
别名 | Hoechst 34580 tetrahydrochloride (23555-00-2 free base), HOE 34580 tetrahydrochloride |
分子量 | 597.41 |
分子式 | C27H33Cl4N7 |
密度 | no data available |
存储 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | H2O: 41.2 mg/mL (68.96 mM), Sonication and heating are recommended. | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
H2O
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